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Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present protocols for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.
- Sales Rank: #2751737 in Books
- Brand: Brand: Humana Press
- Published on: 2006-09-01
- Original language: English
- Number of items: 1
- Dimensions: 9.26" h x 1.07" w x 6.30" l, 1.54 pounds
- Binding: Hardcover
- 312 pages
- Used Book in Good Condition
Review
From the reviews:
"This book forms part of an extensive and successful series from Methods in Molecular Biology … . this book provides a good introduction to metabolomics, with useful protocols and relevant data analysis techniques that can be adapted easily to suit any researcher’s needs." (Elizabeth Want, ChemMedChem, Issue 2, 2007)
From the Back Cover
Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present protocols for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.
Part I of this volume focuses on GC-MS techniques; specifically, attention is given to metabolite profiling in blood plasma, construction and application of mass spectral and retention time index libraries, and metabolomic profiling of natural volatiles. In Part II, emphasis shifts to data integration and data mining techniques, and specific protocols discuss improving pattern recognition and biomarker selection for systems level approaches, and visualization and analysis of molecular and metabolomic data. Parts III, IV, and V examine the coupling of capillary electrophoresis and mass spectrometry, classical reversed phase liquid chromatography-mass spectrometry, and electrochemical detection of metabolites using HPLC separations coupled with coulometric electrode array detectors. In Part VI, protocols for the determination of metabolic flux rates are presented and a theoretical framework for metabolic pathway network analysis is provided. The volume concludes with an examination of cutting-edge NMR protocols.
Most helpful customer reviews
1 of 1 people found the following review helpful.
A Collaboration of Scholarly Approaches to Metabolomics
By Danielle
I bought this book because I'm really getting into the idea of Metabolomics and hoping to branch into it somewhere down the line.
I've been away from university science for some time and wasn't sure what I've been missing in terms of advancements and how the current technology I use may bleed into it.
I found the book to be helpful. Its kinda a specialized book but the format is one more of bringing together research papers into a small volume of work where you have the opportunity to read the many different techniques and protocols in detail based upon a protocol developed in a lab.
Its not a book really meant for those who are just beginning to get involved in metabolomics and the significance of it... nor is it good for someone who has limited experience in laboratory research before.
Its not a bad book, but you may find other books out there to be more appetizing.
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